Dr. Dwayne Jackson

The Vital Science Blog

Starting Living Your Best


We all know that mental stress negatively impacts many facets of life, including work and physical performance, focus, and intensity. Stress also promotes chronically elevated blood cortisol levels, a potent catabolic (muscle wasting) hormone—which impacts immunity and overall wellbeing. 


Research has shown that a patented compound called Relora®, made from Magnolia and Phellodendron barks significantly improves the mood of moderately stressed men and women. In a placebo-controlled trial, scientists reported that stressed subjects, who received Relora®, had a 42% reduction in anger and 13% reduction in tension, a 20% decrease in depression, an 18% increase in vigor, a 31% decrease in fatigue, 27% less confusion, and an 11% increase in mood state. To top it off, the researchers reported an 18% decrease in salivary cortisol levels with Relora® supplementation. So, with Relora® you not only improve your mood, but also improve your hormonal responses to stress [3]. 


How to use Relora to modify your mood: Relora® is a patented extract of Magnolia and Phellodendron barks that have been standardized to not less than 1.5% honokiol and 0.1% berberine. If you are stressed out and are looking to improve mood and want to keep cortisol levels regulated, this study suggests taking 250 mg of Relora with breakfast and another 250 mg with dinner. 



  1. Talbott SM, Talbott JA, Pugh M. Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological mood state in moderately stressed subjects. J Int Soc Sports Nutr. 2013 Aug 7;10(1):37.
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