Dr. Dwayne Jackson

The Vital Science Blog

Starting Living Your Best

Body Shop Jan 2017

Dwayne N. Jackson, PhD

Colostrum is a special form of milk produced by mammals shortly before and after the birth of offspring. Like regular milk, it is high in protein and vitamin A, but has relatively low amounts of fat, carbs, and potassium. The greatest distinguishing feature of colostrum versus regular milk is its very high levels of bioactive growth factors (like IGF-1) and antibodies that promote development of the offspring and provide ‘grassroots’ immunity against pathogens. 

So what does this have to do with fitness? 

Bovine (cow) colostrum, as a supplement, has been around for decades, mainly due to its very high levels of bioactive growth promoting and immune boosting factors/peptides. However, the scientific community is only just realizing its efficacy as an ergogenic aid. The latest research supporting colustrum for promoting muscular growth comes from a study presented last summer (2016) at the 13th International Society of Sports Nutrition (ISSN) Conference and Expo in Clearwater, Florida. In this double-blind, placebo controlled study, the researchers sought to determine the effects of supplements containing either isolated bioactive peptides or whole colostrum on body composition changes induced by a growth promoting strength training regimen. Thirty-two college aged and resistance trained participants were given colostrum, bioactive peptides, or placebo, to be taken daily, during an 8-week structured 4-day split training cycle.  

At the end of 8 weeks, the researchers reported that colostrum supplementation produced the most dramatic effects on increased lean mass (~2.5 kg; 233% over placebo) with no significant change in fat mass (although they report a ‘trend’ for deceased in fat mass and body fat percentage). The authors concluded that the addition of bovine colostrum to a 4-day split resistance program appears to augment lean mass gains better than placebo or a commercially available isolated bioactive peptide supplement.

ACTION POINT: The authors did not specify their supplement dosing in this study, however in order for colostrum to be effective as a muscle builder, you have to take relatively large doses. For best results, we suggest replacing 5-10 g of protein from your pre and postworkout shake with 5-10 g of bovine colostrum. 

Reference: A. Kreutzer, P. Zavala, S. Fleming, M. Jones, J. M. Oliver, A. Jagim. The effects of 8 weeks of colostrum and bio-active peptide supplementation on body composition in recreational male weight lifters. Journal of the International Society of Sports Nutrition 2016 13(Suppl 1):33


Citrulline Malate: Fuel for Females

L-citrulline helps prevent muscle fatigue, as it assists in production of energy by increasing the rate of phosphocreatine and ATP production. Citrulline also converts to arginine (the precursor to nitric oxide) in the kidneys and optimizes blood and nutrient delivery to working muscles. Recent research indicates that citrulline supplements can actually increase blood levels of arginine and nitric oxide more effectively than arginine ingestion. Beyond creating incredible pumps, a single pre-workout dose of citrulline has been shown to combat exercise-induced fatigue, increase time to exhaustion, and substantially decrease muscle soreness. 


While the benefits of taking citrulline supplements are well defined, as with most supplements, few studies include women, thus little is known of its benefits in this cohort. A most recent study, published in the Journal of the International Society of Sports Nutrition, sought to compare the effects of citrulline malate supplementation on lower body muscular endurance in males and females. It was reported that, although performance benefits with citrulline malate were realized in both groups, females experienced increased torque production and work with citrulline malate compared to males. 


ACTION POINT: Males and females, take 6 g of citrulline malate with your preworkout shake approximately 30 minutes preworkout. 

Reference: Joshua L Gills, Hocheng Lu, Kimberly Parker, Chris Dobbins, Joshua N Guillory, Braden Romer, David Szymanski, Jordan Glenn. The effects of acute citrulline-malate on lower-body isokinetic performance in recreationally active individuals. Journal of the International Society of Sports Nutrition 2016 13(Suppl 1):33

Coaching Subscriptions packages

Weight Loss Transformer

Starting at $549.99

Fully Optimized Human (Exclusive access to Dr. Dwayne)

Starting at $1,499.99

Muscle Builder Elite

Starting at $549.99

Coaching The Coach

Starting at $199.99

Gut Health

Starting at $499.99

Optimized Human

Starting at $749.99
Starting Living Your Best

If you’re interested in staying fit, eating healthy, and living a healthier life, then you should join my newsletter! I’ll be sending out regular updates on fitness nutrition and health, so you can stay informed and make the most of your health.

Scroll to Top